May 312008


ISLAMABAD: Patients with type 2 diabetes might be at risk of chronic kidney disease, if they also have non-alcoholic fatty liver disease, according to a new study.

In such cases, “type 2 diabetic individuals … should be targeted with more intensive therapy to decrease their risk of developing chronic kidney disease (CKD)”, said the study’s co-authors Giovanni Targher of the University of Verona, Italy, and Michel Chonchol of the University of Colorado.

The duo studied the links between non-alcoholic fatty liver disease (NAFLD) and CKD in 1,760 adult patients with type 2 diabetes. The former is a common type of chronic liver disease, in which deposits of fat build up in the liver. Over time, NAFLD can progress to more advanced forms of liver disease, including cirrhosis. The study excluded patients with other common causes of fatty liver, such as alcohol abuse, chronic viral hepatitis and use of medications with potentially toxic effects on the liver.

All the patients initially had normal or near-normal kidney function. During an average follow-up period of six and a half years, 547 patients developed CKD, with a yearly risk of about 4.5 percent. The risk of CKD was elevated for patients with NAFLD – 69 percent higher than for patients without NAFLD. The difference remained significant after adjustment for potential risk factors, including age and sex, body fatness, duration of diabetes, hypertension, smoking and medications for hypertension. The findings of the study are slated to be published in the August issue of the Journal of the American Society of Nephrology.

Exercise cuts cancer risk: Men who exercise often are less likely to die from cancer than those who don’t, according to a new study.

The study was based on the effect of physical activity and cancer risk in 40,708 men aged between 45 and 79.

Over the seven-year period of the study, published in the British Journal of Cancer, 3,714 men developed cancer and 1,153 died. Men who walked or cycled for at least 30 minutes daily increased survival from cancer with 33 percent, compared to those who exercised less or did nothing at all.

Researchers also found that a more extensive programme of walking and cycling between 60 and 90 minutes daily led to a l6 percent lower incidence of cancer. But these activities only led to a five percent reduction in cancer rates among the men who walked or cycled for 30 minutes day, a finding that could be ascribed to chance.

The researchers surveyed the men on their lifestyle and the amount of their physical activity. They then scored these responses and compared the results with data officially recorded in a central cancer registry over a seven-year period. “These results show for the first time, the effect that daily exercise has in reducing cancer death risk in men aged between 45 and 79,” said Alicja Wolk of the Swedish Medical University, who led the study. “We looked at more moderate exercise such as housework, undertaken over a longer period and found that this also reduced men’s chances of dying from the disease.”

Active social life delays memory loss: Elderly people who are active socially may delay or have a slower rate of memory loss, according to a new study. Earlier studies have suggested that an active social life may reduce the risk of dementia among elderly. Memory loss is a strong risk factor for dementia, which afflicts millions of elderly globally.

The researchers wanted to test whether memory loss might also be associated with social connectedness.

“We hope this study adds to and advances our growing understanding of the important role that social forces play in shaping health,” said Karen Ertel of Harvard School of Public Health, who led the study.

Ertel relied on data gathered from 1998 to 2004 from the Health and Retirement Study, which surveyed a large, nationally representative population of US adults 50 years and older.

Memory was assessed in 1998, 2000, 2002 and 2004 by reading a list of 10 common nouns to survey respondents, then asking them to recall as many words as possible immediately and after a five-minute delay.

The results showed that individuals with the highest social integration had the slowest rate of memory decline from 1998 to 2004.

  2 Responses to “Diabetes, kidney ailment linked to fatty liver”

  1. My dad has type 2 diabetes. He manages diabetes through Diet and Exercise and alo by taking food supplements like Alpha Lipoic acid which helps in preventing nerve damage. He also takes Chromium which helps in the regulation of blood sugar.

  2. Diabetes may finally have a cure through extensive stem cell research. But for now, diabetes can only be managed by drugs or food supplements that controls blood sugar. I take Alpha Lipoic acid and Chromium because they are helpful in regulating blood sugar.

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